Post-brachytherapy initial tumour regression rate correlates with metastatic spread in posterior uveal melanoma

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Post-brachytherapy initial tumour regression rate correlates with metastatic spread in posterior uveal melanoma.

AIM To confirm the prognostic value of post-brachytherapy initial tumour regression rate in posterior uveal melanoma. METHODS A prospective, comparative, observational cohort study was carried out on 147 eyes (147 patients) with choroidal melanoma (mean age 61 years) treated with Ru-106 brachytherapy. OBSERVATION PROCEDURE Patients were followed clinically and ultrasonically every 6.7 (SD 0...

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SCIENTIFIC REPORT Post-brachytherapy initial tumour regression rate correlates with metastatic spread in posterior uveal melanoma

Aim: To confirm the prognostic value of post-brachytherapy initial tumour regression rate in posterior uveal melanoma. Methods: A prospective, comparative, observational cohort study was carried out on 147 eyes (147 patients) with choroidal melanoma (mean age 61 years) treated with Ru106 brachytherapy. Observation procedure: Patients were followed clinically and ultrasonically every 6.7 (SD 0.3...

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Microincisional vitrectomy for retinal detachment in I-125 brachytherapy-treated patients with posterior uveal malignant melanoma

PURPOSE To analyze functional and anatomical outcomes following 23/25(+) gauge microincisional pars plana vitrectomy surgery (MIVS) in patients with radiation-related retinal detachment after successful 125-iodine (I-125) brachytherapy treatment for malignant uveal melanoma. PATIENTS AND METHODS Retrospective case series of 102 consecutive eyes of 102 patients with history of uveal melanoma t...

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18 years' experience with high dose rate strontium-90 brachytherapy of small to medium sized posterior uveal melanoma.

AIM To analyse local tumour control, radiation related complications, visual acuity, enucleation rate, and survival after brachytherapy of small to medium sized choroidal melanoma (CM) with a high dose rate (HDR) strontium-90 (Sr-90) applicator. METHODS From 1983 until 2000, 98 eyes with CM were treated with Sr-90 brachytherapy. The main outcome measures were actuarial rates of the patients' ...

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Long-Term Survivors with Metastatic Uveal Melanoma

BACKGROUND To report the tumor, patient, and treatment characteristics of long-term metastatic uveal melanoma survivors. METHODS A non-comparative, retrospective case series of patients from a single institution surviving >24 months with metastatic uveal melanoma (UM). RESULTS Nine patients met the study criteria and their charts were reviewed. The mean age at diagnosis of UM was 44.1 years...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2004

ISSN: 0007-1161

DOI: 10.1136/bjo.2003.036285